Thank you for the query.
Fissure can not be treated just with one medicine. There are several things which can together make fissure healed.
First of all you should avoid constipations with diet change and increase physical activity. You should have more fiber rich products and mineral water intake. Fatty foods and soft drinks should be avoided. You should not put pressure on stool as it makes fissure worst.
Sitz baths with Quercus Cortex
twice a day can give great effects. You should also wash your rectum
after every stool and keep it clean.
Lignocaine gel will ease the pain. Nitroglycerine gel will help relax the rectal muscle.
Such treated fissure should get healed in a weak or so.
In some cases when the fissure does not get healed for a long time, surgery might be necessary.
Hope this will help.