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First you should get investigated for cause of low weight as many illness may lead to weight loss
. Apart from that depression
itself, can lead to poor appetite
and weight loss.
Vice versa low weight lead to decrease self esteem and depression.
You should also go thyroid
function test as its dysfunction may lead to both depression and weight loss. It is also more common in middle aged female.
I hope this information has been both informative and helpful for you.
Wish you Good Health.
Dr. Ashish Mittal