Hello, and I hope I can help you today. It sounds like your patient has some form of liver disease, and she has been exposed to Hepatitis B. If she wants to terminate the pregnancy, there should not be any issues other than determining if she is clotting normally before the procedure, so I suggest checking a PTT and an aPTT and platelet count beforehand and a discussion with the anesthesiologist before her procedure about the best medications to use. Then after 6 weeks from the termination I would refer her to a liver specialist for treatment. However there is no reason she should need to terminate the pregnancy as long as she is able to get a full evaluation and careful maintenance of her liver disease. She likely has active hepatitis B, to determine how active, she needs (at a minimum) a screen for hepatitis A and C, a measure of the other hep B antibodies (E and core), an ultrasound of her liver, and a consultation with a liver specialist. In New York in the US where I live, there are a lot of immigrants from China who were chronic Hep. B carriers and I have seen two women go into acute liver failure during pregnancy, so this can be very serious, even needing a liver transplant. In addition the risk of exposure at birth for the baby is possible; as long as the baby receives HbIG at birth, and then the Hep B vaccine immediately after birth everything should be OK. If the hospital where you practice does not offer these treatments, I suggest you refer your patient to a perinatalogist to care for her during the pregnancy as this is a high-risk situation. I hope this advice was helpful and best of luck with this patient. Regards, Dr. Brown