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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is It To Be Concerned About The Total Bilirubin Level In The Liver Function Test?

Dear Doctor Last week i did liver Function test. and please find the result below Test Description Observed Value Reference range & Units Biochemistry Bilirubin-Total (Serum/Diazo) 1.5 0.2 - 1.0 mg/dl Bilirubin-Direct (Serum/Diazo) 0.2 Enzymes SGOT(AST) (Serum/Kinetic/IFCC) 23 15 - 37 U/L SGPT(ALT) (Serum/Kinetic/IFCC) 45 30 - 65 U/L Alkaline Phosphatase (Serum/Kinetic/PNPP) 83 50 - 136 U/L Gamma GT (Serum/Kinetic) 31 15- 85 U/L Proteins Total Protein (Serum/Biuret) 7.1 6.6 - 8.8 gm/dl Albumin (Serum/BCG) 4.1 3.4 - 5.0 g/dl Globulin (Serum/Calculation) 3.0 2.3 - 3.5 gm/dl A/G Ratio (Serum/Calculation) 1.40 Electrophoresis is the preferred method Still my total Bilirubin level is high but all other showing normal. how to reduce total Bilirubin level ? any medicine needs to be taken ? last month my total Bilirubin is 1.7 and Alkaline Phosphatase (Serum/Kinetic/PNPP) 59 .. now total bilirubin level reduced but SAP vaule got increased from 59 to 83... Note : few months back i got affected by viral fever. that time total bilrubin is normal. after a month i got chest pain and i went another hospital they ask me to take LFT, that time Total bilrubin level is 1.1( normal 1.0 in that hospital) doctor told me this is is normal no need to take any medicine. but now its showing 1.5. why its gradually increasing. and i did ultrasound in my liver. all are in normal condition.. what i need to do . please help me out how to decrease the total bilirubin level. and i never smoke and drink... now a days i am not taking oily foods Please help me out..
Mon, 5 Feb 2024
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Gastroenterologist 's  Response
Hi,

My opinion is that you should not worry about very mild increase in bilirubin. 1.5 and 1.7 bilirubin are mild increase in levels. Possible reasons must be Recent history of fever, Fasting state, Intake of medication and most commonly Gilbert syndrome. As our body will be in dynamic state, little bit of fluctuations are expected.

I would suggest you to get done genetic testing for Gilbert syndrome. UGT1A1 Gene polymorphism. Regarding Alkaline phosphatase, although it has increased from 59 to 83 but still it is in the normal range only (50-136).

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Pavan Kumar, Gastroenterologist
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Is It To Be Concerned About The Total Bilirubin Level In The Liver Function Test?

Hi, My opinion is that you should not worry about very mild increase in bilirubin. 1.5 and 1.7 bilirubin are mild increase in levels. Possible reasons must be Recent history of fever, Fasting state, Intake of medication and most commonly Gilbert syndrome. As our body will be in dynamic state, little bit of fluctuations are expected. I would suggest you to get done genetic testing for Gilbert syndrome. UGT1A1 Gene polymorphism. Regarding Alkaline phosphatase, although it has increased from 59 to 83 but still it is in the normal range only (50-136). Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Pavan Kumar, Gastroenterologist