Hi Lisa, Welcome and thanks for posting your query to HCM. Definitely the product which you are using is working better as are shrinking down with the application the medication, but you have to understand the fact that genial area is very very sensitive area so by any chance the medication is applied in higher amount or is applied on normal mucosal or skin area then can cause burns at that site. As this magic cream contains Podophyllin, Salicylic acid and Benzoin tincture- amongst all of three Podophyllin is the resin which is working the best for genital warts, but is the most important compound to cause both systemic which may prove to be serious and local side effects burning, redness, pain, itching, swelling and even ulceration. We generally do not give the medicine directly to patient and demonstrate its usage, once we are confident then only is advised for self medication. Are you applying it under medical guidance or as self medication, if not under medical guidance then be very careful in applying or must see the doctor who can explain and can watch the progress of the healing. If you are not able to see the doctor then should apply the least of amount ( no spillage) should be washed after 10minutes of application and application of petroleum gelly around the normal skin surrounding wart. If you feel pain or redness then stop the application for few days or any other side effect mentioned then must see the doctor. With best health wishes and do take care, Dr Sanjay K Kanodia MD ( Dermatology and STD/ Venereology)