These are all good questions. Past the age of menopause, and especially if no HRT has been used, the endometrial stripe thickness on
ultrasound should be 4mm or less. Any measurement greater than 4 mm is a concern for the development of
endometrial cancer. Therefore, prior to performing a
hysterectomy, a biopsy of the tissue lining the uterus needs to be performed. The gold standard for that evaluation is
hysteroscopy with D&C. An office biopsy may or may not be definitive. If cancer is found, then hysterectomy is appropriate, probably with a Gyn
Oncologist so that the proper staging hysterectomy can be performed. Staging is important for future management of
uterine cancer.
I have seen patients who proceeded to hysterectomy directly with this scenario and were found to have cancer. Without proper staging at the original hysterectomy, they had to either undergo a further surgical procedure or opt for treatments that were recommended by assuming the cancer had spread beyond Stage 1.
When addressing the ovary, it may help to have a CA 125 level drawn. An elevation of that level is not specific for
ovarian cancer (it can be elevated from fibroids, for instance) but is worrisome, which again would lead me to refer you to a Gyn Oncologist. A normal CA 125 level would be reassuring that you are not dealing with a developing ovarian cancer.
Given the situation you are dealing with, I believe you would be best served by a consultation with a Gyn Oncologist prior to making your final decisions. Hopefully, the concerns you express can be addressed at that initial consultation and you will be comfortable with your decision making process.
I hope this helps you answer your questions. I am available for further consult if needed.