Hello Ms Suparna, Thank you for asking at HCM. I went through your son s history. Both Asthalin and Duolin are rescue drugs for asthma. They are used when child as an asthma attack/worsening of asthma. Duolin contains two drugs - salbutamol (same as Asthalin) and ipratropium bromide. Practically, if your son responds well to Asthalin inhaler, I would suggest you to continue it on as and when required basis . When symptoms are more/attack is severe, it is advised an additional drug such as ipratropium bromide (as in Duolin). However, most attacks can be well managed with Asthalin only. I want to emphasize one thing that if he needs to use Asthalin approximately more than twice a week or he has night-time/early morning cough more than once a week, that suggests his asthma is not well controlled. So using regular controller medications like montelukast or inhaled corticosteroids is highly recommended. Also, as he is having mostly night/early morning symptoms, I would think of house dust mite or mold or cockroach allergy. So I would suggest you to consult an Allergist-Immunologist who will suggest him allergy testing and advise accordingly. As general measures, I would suggest yo avoid dusts, smokes, cold air currents and air-pollution as much as possible. If he can perform regular breathing exercises, Yoga and Pranayama, that will help him a lot in a long run. I would also suggest him a nutritious diet rich in vitamins, minerals and anti-oxidants. I would suggest his bed room to be warm and well-ventilated, however, more recommendations can be made on basis of allergy testing only. Hope this will be helpful to you. Wish your son the best of the health. Regards.