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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Have Developed Blisters And Sugar Lowered After Taking Metformim. What Dosage To Continue With Damaged Liver?

I have been taking Metformim for two weeks doctor has me taken 1 pill at night for 1 to 2 weeks. Since I started this I have small blisters on my hands. My blood sugar has decreased from 240 down to 140 or 130 in the mornings and lowers during the day tonight it was 114. I'm afraid to take 2 pills at night as she instructed as I already have liver damage and am afraid my sugar will go to low. Should I take the two pills? Will the blisters go away?
Tue, 3 Dec 2013
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Internal Medicine Specialist 's  Response
Hi there,

Thanks for your query.

Firstly, Metformin has brought down your blood sugar to within desirable range, though the morning (empty stomach) blood sugar is still high. There is thus, a need of increasing the dose of metformin; or, addition of another drug.

Metformin is detoxified and thrown out of the body predominantly by the kidneys. Hence, mild liver damage in not a contraindication of stopping metformin.

Lastly, it is probably a coincidence that you developed blisters on the hand after you started metformin. These blisters are probably viral and need a course of anti-viral agents.

Consult your doctor and apprise him of my opinion. I am certain that he will agree with me, order required tests, and- based on the reports- will prescribe suitable/modified treatment as advised.

In case of any further queries, revert back to me THROUGH DIRECT PREMIUM QUERY (Paid), addressed to me personally. You will receive- almost immediately- my response in great details.

If you find my response helpful and informative, do not forget an “excellent” (5-star rating) to my answer, to ENCOURAGE all doctors- engaged in social service- to render sound advice to the FREE queries.

Fond regards and have a nice day

Dr. Rakesh Karanwal
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Have Developed Blisters And Sugar Lowered After Taking Metformim. What Dosage To Continue With Damaged Liver?

Hi there, Thanks for your query. Firstly, Metformin has brought down your blood sugar to within desirable range, though the morning (empty stomach) blood sugar is still high. There is thus, a need of increasing the dose of metformin; or, addition of another drug. Metformin is detoxified and thrown out of the body predominantly by the kidneys. Hence, mild liver damage in not a contraindication of stopping metformin. Lastly, it is probably a coincidence that you developed blisters on the hand after you started metformin. These blisters are probably viral and need a course of anti-viral agents. Consult your doctor and apprise him of my opinion. I am certain that he will agree with me, order required tests, and- based on the reports- will prescribe suitable/modified treatment as advised. In case of any further queries, revert back to me THROUGH DIRECT PREMIUM QUERY (Paid), addressed to me personally. You will receive- almost immediately- my response in great details. If you find my response helpful and informative, do not forget an “excellent” (5-star rating) to my answer, to ENCOURAGE all doctors- engaged in social service- to render sound advice to the FREE queries. Fond regards and have a nice day Dr. Rakesh Karanwal