Hi and thanks for the query, persistent diarrhea needs a careful review and evaluation notr only because it could lead to dehydration, but could actually cause malnutrition with adverse consequences on the body s immune system and other organs. It would be very appropriate to know when this diarrhea actually started and the various therapies that have been tried. Diarrhea with increased temperature and cramping gives a suggestion of an infectious process. Its mandatory in this case to do a stool examination, culture and sensitivity tests to identify the causative organism and probable antibiotic that could be effective on this organism. Blood cultures, complete blood counts, C reactive protein levels are initial tests of importance that could give great insight into the possible cause of these symptoms. Viruses could also be implicated, but cause chronic diarrheas mainly in immunodepressed populations like Cytomegalovirus. Other parasites like cryptopsporidium, Isospora cause diarrhea under similar circumstances. Doing a routine HIV test could also be advisable. I strongly advise you seek the opinion of your gastroenterologist or internist. Best regards, Bain LE, MD.