I have a family member who is currently in ICU. Last Sunday, she was placed on a ventilator and removed from the vent a couple of days later. Currently, she has been decreased from 60L of high flow oxygen to 40L (they are trying to wean her from the high flow oxygen). While resting, she is tolerating the weaning process well. Her O2 saturation remains in the high 90s to 100 and her blood gases are improving and from my understanding, acceptable. However, if she is turned or physically moved up in the bed, etc., her numbers (mainly her O2 saturation) bottoms out and it takes her anywhere from 30 minutes to as long as an hour to recover and get her numbers back up. The doctors and nurses are telling us that they do not know why this is happening. To me, that is very concerning. Could you offer any insight as to why this is happening? She has been diagnosed with COPD (related to smoking) and was not on any oxygen therapy prior to being admitted into the hospital. They did state that her lungs have suffered extensive damage and when I asked how extensive, they could not tell me because she was unable to perform a PF test. She had an upper respiratory infection, which led to her going to the ER initially.