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What Does This Blood Report Indicate?

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Posted on Mon, 17 Oct 2016
Question: My name is XXXXXXX and I am doing this consultation for my Son who is just 18 days old. My son has congenital hypothyroidism detected on the 3rd day after his birth. His TSH level was > 100 and FT4 was 0.58. As advised we have done a thyroid scan on 3rd day after his birth, result is attached. As per the result it is thyroid organification defect.

As doctors prescribed we have started electroxin 45mg ( 50 mg will be dissolved in 5 ml milk and and giving 4.5 ml to baby).

on 13th day after his birth, we have performed thyroid test (TSH, Ft4) again and the TSH came down to 28.55 and ft4 went up to 2.92

I would like to get clarified few this here for the betterment of my baby:-

1) Do he need to take medication for his life long ? how much chance of stopping medicine after 3 years
2) Any sideeffect/affter effect for this medication ?
3) are we giving the right dose to baby ?
4) how long it will take TSH to comedown to normal values in normal case
5) Doctor suggested an echo test as he felt a mild murmur during a routine examine, hope that is not serious ?

Please please verify the test results attached and help me
doctor
Answered by Dr. Sumanth Amperayani (28 hours later)
Brief Answer:
Suggestions on congenital hypothyroidism

Detailed Answer:
Hi....I have gone through your baby's reports -

1. Failure of organification or organification defect refers to an enzyme deficiency or insufficiency in the thyroid gland. This might require a lifelong treatment. Sometimes insufficiency may get better, but it is rare.

2. After 3 years as the brain neuronal organization would have been completed, we can stop the thyroid supplements for a month and check the thyroid status and decide on further management.

3. If appropriate dose is used side effects are minimal. Nothing to worry. This is a safe medication.

4. I can tell you about the dose appropriateness if you can get back to me with the exact weight of the baby as the doses in kids are measured as per weight.

5. It can take 2 weeks to 4 weeks.

6. Please get the echo done and get back to me with the report. Without the echo report, I cannot tell whether it is serious or not based on murmur alone.

7. I also suggest you get the baby's hearing checked by BERA test as hearing loss is sometimes associated with organification defect of the thyroid gland.

Regards - Dr. Sumanth
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Sumanth Amperayani (5 hours later)
Thank you Doctor,

His weight is 2.9 KG
doctor
Answered by Dr. Sumanth Amperayani (1 hour later)
Brief Answer:
The dose is perfect

Detailed Answer:
Hi....the dose is perfect. Don't worry.
Regards - Dr. Sumanth
Note: For more information on hormonal imbalance symptoms or unmanaged diabetes with other comorbid conditions, get back to us & Consult with an Endocrinologist. Click here to book an appointment.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Sumanth Amperayani

Pediatrician, Pulmonology

Practicing since :2003

Answered : 8339 Questions

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What Does This Blood Report Indicate?

Brief Answer: Suggestions on congenital hypothyroidism Detailed Answer: Hi....I have gone through your baby's reports - 1. Failure of organification or organification defect refers to an enzyme deficiency or insufficiency in the thyroid gland. This might require a lifelong treatment. Sometimes insufficiency may get better, but it is rare. 2. After 3 years as the brain neuronal organization would have been completed, we can stop the thyroid supplements for a month and check the thyroid status and decide on further management. 3. If appropriate dose is used side effects are minimal. Nothing to worry. This is a safe medication. 4. I can tell you about the dose appropriateness if you can get back to me with the exact weight of the baby as the doses in kids are measured as per weight. 5. It can take 2 weeks to 4 weeks. 6. Please get the echo done and get back to me with the report. Without the echo report, I cannot tell whether it is serious or not based on murmur alone. 7. I also suggest you get the baby's hearing checked by BERA test as hearing loss is sometimes associated with organification defect of the thyroid gland. Regards - Dr. Sumanth