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What Does My Lab Test Report Indicate?

Posted on Tue, 14 Feb 2017

Question: Hello. My mother lives in Dominican republic she had zika virus real bad and just got this lab results indicating gammapathy monoclonal type igg lambda and i have been reading and sounds really bad. So my question is. 1. Is it cancer? 2. If so is she dying or will do? And i have seen some of tests talking about citamegalovirus and ep barren virus. What does it have to do with the gammapathy m?
Im a little work out would appreciete a quick response and sorry for the way i write. Im desperate.

Thanks

Answered by Dr. Indranil Ghosh (3 hours later)

Brief Answer:
Not very serious

Detailed Answer:
Hi
Thanks for your query.

At this age monoclonal gammopathy is not uncommon. It doesn't always need treatment or cause any problems. In her the exact level of gamma monoclonal protein is not mentioned. But probably it is very low as the total gamma is mentioned as 1.3. Hence it will be less than this.

Her hemoglobin is normal, if calcium, creatinine are also normal with no damage to bone, then no treatment required.

Her tests are suggestive of old epstein barr virus and cytomegalovirus infection. Many people have this. Association with monoclonal gammopathy is there but doesn't influence treatment.

She needs to follow up with a hematologist or oncologist for further plan.

Hope this helps.
Regards

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Indranil Ghosh (12 minutes later)

Thank you doctor. You made me calmer.
So for what i sent you is she gonna be ok or is it cancer and will haver serious problems soon?
Thanks

Answered by Dr. Indranil Ghosh (31 minutes later)

Brief Answer:
Doesn't look like that

Detailed Answer:
First we need to see if it is just gammopathy or myeloma. For that calcium, kidney function and bone screening should be done. if these are normal then it is not cancer. But over time, 10% may progress to myeloma, which is cancer. But even that is controllable with treatment.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Indranil Ghosh (20 minutes later)

Ok doc. She suffers a little of stones in the kidneys wich she expulses from her urinary track. Will this affect the kidney function test regarding the diagnosis we are trying to establish?and second when you say bone screening do you mean a ct scan or magnetic resonance?
And lastly for what you are saying this situation is controlable and in case of myeloma she still has chance to live

Thanks again. Youre almost done with me doc. ?

Answered by Dr. Indranil Ghosh (2 hours later)

Brief Answer:
Stones should not influence

Detailed Answer:
stones should not influence kidney function unless blocks outlet of kidneys.

Bone screening means xrays. If required then only CT or MRI.

If monoclonal gammopathy without myeloma, then no treatment required. Only observation. if myeloma, then treatment required, which will keep it under control.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Indranil Ghosh (2 days later)

Thanks doc. I just sended some new lab tests and the calcium and anemia is fine. We did some ct scan of her spine(back) and brain and no litic lesions found on her bones plus other blood tests. She lso has her kidney functions fine. And the hematoncologist said her m spike was less than 3. Which wasnt high enough to suspect mm. With this findings do you agree could only be mgus? She will nevertheless do the biopsy in the bone later this week. What do you think? Please give me some hope. Thanks for everything doc.

Answered by Dr. Indranil Ghosh (5 hours later)

Brief Answer:
This is MGUS

Detailed Answer:
This is not myeloma, based on these reports. So no treatment will be required at present. There is nothing to worry.

Note: Do you have more questions on diagnosis or treatment of blood disorders? Ask An Expert/ Specialist Now

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar