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What Does My AMH Test Report Indicate?

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Posted on Fri, 31 Jul 2015
Question: My wife went through an AMH test today.
The report is as follows,
Investigation - Anti Mullerian Hormone (AMH) (Serum)
Findings - 7.63
Method - ELISA

As per the reference range given in the report it says,
High Levels > 6.79 ng/ml (? PCOD / Granulosa cell tumours)

Could you please tell if 7.63 is within the accepted range for pregnancy?
Is the word 'Granulose cell tumour' something we should be worried/concerned of?
We're trying for pregnancy.
Her periods are irregular too.
Please suggest what should be done to bring the AMH level(if at all) within acceptable range.
doctor
Answered by Dr. Sameer Kumar (16 minutes later)
Brief Answer:
PCOD

Detailed Answer:
Hello,
Thanks for the query to hcm,
A high AMH levels of more than 7 with a history of irregular periods indicate that she is possibly a case of PCOD or polycystic ovarian disease , with anovulatory cycles. PCOD with anovulatory cycles can cause delayed menses or even amenorrhoea for long. it is suggested that a ultrasound pelvis be done to rule out polycystic ovaries and hormonal profile for hyperandrogenemia.
Granulosa cell tumour is not usually seen and can be diagnosed with very high levels of hcg .
This is more of a case of PCOD than anything else.
Regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Sameer Kumar (23 hours later)
Thanks for the reply. Yes, the ultrasound test was done and and it showed enlarged ovaries having multiple tiny follicles. I've attached the ultrasound report here too. Please suggest a remedy as we have consulted many doctors and every one asks us to go through a lots of tests but no concrete solution.Please let us know the solution to get pregnant.
doctor
Answered by Dr. Sameer Kumar (1 hour later)
Brief Answer:
PCOS OR POLYCYSTIC OVARIAN DISEASE.

Detailed Answer:
Hello,
This is definitely PCOD , where the volume of ovaries is 20cc, way above normal( 10cc), with multiple follicles in both ovaries.
signs of PCOD:-
1. HIRSUTISM
2. ACNE
3. ACANTHOSIS NIGRICANS ( darkening of skin behind neck and knuckles) , all indicate hyperandrogegism or excess testosterone production.
4. OBESITY, this causes increased insulin resistance which causes no ovulation and no release of eggs.

So , all have to be controlled together.
1. Weight has to be reduced.
2. She has to be placed on TAB GINETTE 1 OD continuously for atleast 3-4 months to regularise her hormonal balance and her menses.
3. tab metformin 500mg twice a day daily continuously to decrease insulin resistance after getting a serum insulin test done.

You have to be patient here and unless there occurs ovulation, pregnancy chances are bleak. So firstly androgen levels have to be decreased and weight has to be reduced.
Pregnancy should not be planned as failure rate would be anyways high. So meet a gynecologist who can chart a diet plan , exercise plan and place you on regular low dose oc pill ginette along with metformin tabs, as all are available only on prescription.
Regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Sameer Kumar

OB and GYN Specialist

Practicing since :2002

Answered : 1782 Questions

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What Does My AMH Test Report Indicate?

Brief Answer: PCOD Detailed Answer: Hello, Thanks for the query to hcm, A high AMH levels of more than 7 with a history of irregular periods indicate that she is possibly a case of PCOD or polycystic ovarian disease , with anovulatory cycles. PCOD with anovulatory cycles can cause delayed menses or even amenorrhoea for long. it is suggested that a ultrasound pelvis be done to rule out polycystic ovaries and hormonal profile for hyperandrogenemia. Granulosa cell tumour is not usually seen and can be diagnosed with very high levels of hcg . This is more of a case of PCOD than anything else. Regards