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What Causes Sudden Onset Of Severe Knee Pain?

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Posted on Sat, 14 Jun 2014
Question: My wife is having severe pain in her Knees since last 4-5 days. Initially she was having urine infection for which she took medication and from next day the knee pain started. We showed the gynec today but she said that it was not happening because of the medicines.

Can you advice reason why this is happening and what needs to be done. She is going through pain when she is folding her legs.
doctor
Answered by Dr. Bhagyashree.B (1 hour later)
Brief Answer:
stop levofloxacin immediately.

Detailed Answer:
Dear XXXXXXX
Thanks for writing to healthcare magic.
The sudden onset of pain that you mentioned can occur with levofloxacin.
the drug is known to cause tendon and cartilage inflammation in rare cases.
Though I cannot tell for sure that it is a sideeffect of the drug as she may have general malaise due to fever and infection , the sudden onset and severe pain indicates that it is knee joint/ tendons inflammation due to Levofloxacin
Please stop the drug and visit a orthopedic surgeon.
Meanwhile paracetamol 650 mg twice a day and warm compresses will keep the pain in control.
Please write back if you have any query.
Thanks
Dr Bhagyashree
Above answer was peer-reviewed by : Dr. Vinay Bhardwaj
doctor
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Follow up: Dr. Bhagyashree.B (10 minutes later)
Thanks, should I replace it with some other tablet, pls advice.

She is not having any fever since day 1. After starting the said medicines the pain caused by urine infection disappeared from day 2.
doctor
Answered by Dr. Bhagyashree.B (1 hour later)
Brief Answer:
amoxicillin is good replacement

Detailed Answer:
Dear member,
Thanks for writing.
If your wife had completed 5 days of therapy then there is no need for any replacement as the urine infection will be treated.
The amoxicillin is a good drug for urine infection.
As it's a penicillin group of drug some patients may have allergic reaction.
So physical examination by physician and prescription is necessary.
Thanks
Dr Bhagyashree
Note: Revert back with your gynae reports to get a clear medical analysis by our expert Gynecologic Oncologist. Click here.

Above answer was peer-reviewed by : Dr. Vinay Bhardwaj
doctor
Answered by
Dr.
Dr. Bhagyashree.B

OBGYN

Practicing since :2000

Answered : 788 Questions

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What Causes Sudden Onset Of Severe Knee Pain?

Brief Answer: stop levofloxacin immediately. Detailed Answer: Dear XXXXXXX Thanks for writing to healthcare magic. The sudden onset of pain that you mentioned can occur with levofloxacin. the drug is known to cause tendon and cartilage inflammation in rare cases. Though I cannot tell for sure that it is a sideeffect of the drug as she may have general malaise due to fever and infection , the sudden onset and severe pain indicates that it is knee joint/ tendons inflammation due to Levofloxacin Please stop the drug and visit a orthopedic surgeon. Meanwhile paracetamol 650 mg twice a day and warm compresses will keep the pain in control. Please write back if you have any query. Thanks Dr Bhagyashree