HealthCareMagic is now Ask A Doctor - 24x7 | https://www.askadoctor24x7.com

question-icon

What Causes Persistent Anxiety Despite Taking Celexa?

default
Posted on Wed, 16 Aug 2017
Question: I have a long history of panic disorder. For 20 or so years I've been on prozac usually 20 mg. I have several relapses that were always treated the same way double the prozac, therapy, a short 4 or 5 month course of klonopin, and when symptoms subsided I would eventually return to 20 mg. of prozac. This April I had what has turned into my worst relapse. I could feel my anxiety building for the first time in many years, know I was heading into relapse, one Saturday morning in anticipation of seeking out a psychiatrist I took 40 mg of prozac. That night I had terrible heart palpitations and will never know if it was the med or my head. Next morning I went to urgent care for ekg and follow up halter monitor that were both fine, but figured I better get checked out as this was the first panic attack episode in my 50s. My GP sent me to find a psychiatrist, kept stressing that prozac was the most agitating of the antidepressants and I should change. Find a psychiatrist, he put my on klonopin 1mg, and Ambien CR for sleep, didn't touch the prozac 20 mg. dosage. Four weeks later my GP sends me back, "you're now on two extra medcations, because one failed. Ask for something less agitating (even though I've been on prozac 20 years" So with the confusion that this psychiatrist had done nothing about the antidepressant and my doctor pushing me I reluctantly changed to celexa. 4 weeks later at the follow up when I explained that I had increased anxiety and anxiety attacks he wanted to add effexor XR 75, and risperdal .25. The combination of the ssri and snri confused me and the pharmacist. This was not meant to be a change of meds but a combination. So I sought out a 2nd opinion from a psychiatrist at the center where I am in therapy. He thought my GM should not have been involved in the first place, was reluctant to go back to square one with the prozac, and decided to up the celexa to 40mg. So here I am 1 week of celexa at 10 mg. during prozac cross taper, 5 weeks at 20 mg., and 3 weeks at 40 mg. Slight improvement in depression, no change in anxiety, becoming more agoraphobic each day. Lots of avoidance. He wants to give the celexa 2 more weeks at this dose, but is not sure its the med for me. I am supposed to resume teaching elementary school in 3 weeks and am terrified I'll be going through the start up symptoms of a new med at the beginning of the school year. Looking for suggestions on possible course of action.
doctor
Answered by Dr. Seikhoo Bishnoi (46 minutes later)
Brief Answer:
Fluoxetine is better choice than Celexa

Detailed Answer:
Hello thanks for asking from healthcaremgaic.com

I can understand your concern. Coming directly on your doubts-

You are on Celexa since last 9 weeks and there is not much improvement. You are taking 40 mg dose which is an adequate dose of drug for last 3 weeks and there is not much improvement. Anxiety is still persisting and agoraphobic symptoms are there. In that case I'd recommend you to go on Fluoxetine again.

Since Fluoxetine has worked in past and controlled your symptoms effectively so better to move on this drug again rather than taking a mixture of many medicines.

Yes for immediate relief of anxiety and depression symptoms low dose Risperidone or Olanzapine can be added. This will help to augment the effect of Fluoxetine.

You can talk with your psychiatrist for this change and you will definitely feel better.

Low dose benzodiazepines like Xanax or Klonopin could be added to be taken on SOS basis and this will help in relief of anxiety exacerbations.

Thanks and Take care
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
default
Follow up: Dr. Seikhoo Bishnoi (22 minutes later)
Thank you. You were so helpful with your last answers too. Yes at this point the Celexa still is not working well, though I am very frightened by the start up of Fluoxetine deep down it feels like an old friend. I wish I had never changed. The first psychiatrist did nothing about the antidepressant until pushed, so I feel like I've wasted 3 months that would have been better spent with a simple increase in the prozac originally. Can you suggest the cross taper back to prozac?
doctor
Answered by Dr. Seikhoo Bishnoi (16 minutes later)
Brief Answer:
Yes cross tapering will be needed

Detailed Answer:
Hello again

Yes I suggest to cross taper the drugs which will prevent any withdrawal.

You can go to Celexa 30 for a couple of weeks and then Celexa 20 with Fluoxetine for about a week followed by Celexa 10 and Fluoxetine 40 if needed for one more week. After that you can stop the Celexa completely and continue to take Fluoxetine 40 mg till you feel better.

Once your anxiety is controlled totally then the dose can be reduced again to 20 mg.

Thanks.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
default
Follow up: Dr. Seikhoo Bishnoi (9 minutes later)
How much fluoxetine at Celexa 20?
doctor
Answered by Dr. Seikhoo Bishnoi (17 minutes later)
Brief Answer:
Dose equivalence of Fluoxetine to Celexa

Detailed Answer:
Hello again

There is no clear cut comparison for these drugs but roughly 20 mg of Fluoxetine is equal to 20 mg of Celexa. Higher limit of Celexa for depression is 40 mg while fluoxetine can be used to 60-80 mg.

Thanks
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
default
Follow up: Dr. Seikhoo Bishnoi (1 hour later)
Sorry I meant specifically on your cross taper schedule you omitted how much fluoxotine for the 20 mg celexa week.
doctor
Answered by Dr. Seikhoo Bishnoi (7 minutes later)
Brief Answer:
Fluoxetine 20 at Celexa 20

Detailed Answer:
Hello again

Ok, I couldn't understand that.

Take Fluoxetine 20 at Celexa 20 mg. Then Fluoxetine 40 and Celexa 10.

I hope this clears the doubt.

Thanks
Note: For further guidance on mental health, Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Seikhoo Bishnoi

Psychiatrist

Practicing since :2007

Answered : 5193 Questions

premium_optimized

The User accepted the expert's answer

Share on

Get personalised answers from verified doctor in minutes across 80+ specialties

159 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction
What Causes Persistent Anxiety Despite Taking Celexa?

Brief Answer: Fluoxetine is better choice than Celexa Detailed Answer: Hello thanks for asking from healthcaremgaic.com I can understand your concern. Coming directly on your doubts- You are on Celexa since last 9 weeks and there is not much improvement. You are taking 40 mg dose which is an adequate dose of drug for last 3 weeks and there is not much improvement. Anxiety is still persisting and agoraphobic symptoms are there. In that case I'd recommend you to go on Fluoxetine again. Since Fluoxetine has worked in past and controlled your symptoms effectively so better to move on this drug again rather than taking a mixture of many medicines. Yes for immediate relief of anxiety and depression symptoms low dose Risperidone or Olanzapine can be added. This will help to augment the effect of Fluoxetine. You can talk with your psychiatrist for this change and you will definitely feel better. Low dose benzodiazepines like Xanax or Klonopin could be added to be taken on SOS basis and this will help in relief of anxiety exacerbations. Thanks and Take care