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Suggest The Ideal Dosage For NAC

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Posted on Thu, 28 Jul 2016
Question: I am a 21 year old woman suffering from symptoms of both PCOS and OCD condition. I bought 600 mg of NAC (N-Acetylcysteine) supplements for these conditions (since I've heard that NAC is helpful in reducing the symptoms of both the conditions). Also I am a bit overweight (I weigh about 74 kgs to 80 kgs). So my question is how much dosage of 600mg of NAC should I take despite my weight of right now?
doctor
Answered by Dr. Alexander H. Sheppe (4 minutes later)
Brief Answer:
Consultation

Detailed Answer:
Hello, and thanks for your question.

For OCD, doses of NAC that have been used in case reports on the subject recommend going as high as 3000mg daily. However, this needs to be uptitrated carefully to avoid side effects of too much NAC too quickly. I recommend starting with 600mg, and increasing by 600mg weekly until you arrive at a maximum dose of 3000mg. In other words:

Week 1: 600mg
Week 2: 1200mg
Week 3: 1800mg
Week 4: 2400mg
Week 5: 3000mg

Please remember to rate and close this answer thread when you are finished and satisfied.

Above answer was peer-reviewed by : Dr. Prasad
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Follow up: Dr. Alexander H. Sheppe (8 minutes later)
Thank you for the reply doctor, but I am also worried that whether will it work on me with/without side effects, despite of my weight right now?
doctor
Answered by Dr. Alexander H. Sheppe (4 minutes later)
Brief Answer:
Followup

Detailed Answer:
Typically NAC does not have significant side effects. Even given your weight, I would not expect side effects to be a problem. But to be on the safe side, I would follow the above titration schedule to be safe.

Please remember to rate and close this answer thread when you are finished and satisfied.


Above answer was peer-reviewed by : Dr. Yogesh D
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Follow up: Dr. Alexander H. Sheppe (9 hours later)
So doctor, based on the week and its specific amount of NAC for that week given by you, how many capsule(s) a day of NAC should I take to reduce symptoms off both my conditions of PCOS and OCD
doctor
Answered by Dr. Alexander H. Sheppe (4 hours later)
Brief Answer:
Followup

Detailed Answer:
Week 1: 1 600mg capsule per day
Week 2: 2 600mg capsules per day
Week 3: 3 600mg capsules per day
Week 4: 4 600mg capsules per day
Week 5 and after: 5 600mg capsules per day

Please remember to rate and close this answer thread when you are finished and satisfied.

Note: For further guidance on mental health, Click here.

Above answer was peer-reviewed by : Dr. Vaishalee Punj
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Answered by
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Dr. Alexander H. Sheppe

Psychiatrist

Practicing since :2014

Answered : 2236 Questions

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Suggest The Ideal Dosage For NAC

Brief Answer: Consultation Detailed Answer: Hello, and thanks for your question. For OCD, doses of NAC that have been used in case reports on the subject recommend going as high as 3000mg daily. However, this needs to be uptitrated carefully to avoid side effects of too much NAC too quickly. I recommend starting with 600mg, and increasing by 600mg weekly until you arrive at a maximum dose of 3000mg. In other words: Week 1: 600mg Week 2: 1200mg Week 3: 1800mg Week 4: 2400mg Week 5: 3000mg Please remember to rate and close this answer thread when you are finished and satisfied.