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Suggest Remedy For High Testosterone Level In Blood
Question: Dear Dr, I had POS and high testosterone in youth, was on a pill diane 3 only for 3 months. Now 35 have severely diminished ovarian reserve. Had 3 IVF cycles - always produced 6 eggs. Fert rate 60-70%. Consider my treatment was wrong as I had "short" ivfs, 1 cycle was on menopure, had 1 month of DHEA 50 daily, 2 months on combined contraceptive pill with 1 mg norethisterone and 0.5 mg ethinyloestradiol. How can I reverse the damage done by excessive testosterone? Thank you
Brief Answer:
PGS is a better option
Detailed Answer:
Hi,
I understand your concerns about low egg reserve.
The damage is not due to excess testosterone.
You seem to have low egg reserve for your age which is seen in many women.
It is not possible to reverse this aging effect or improve the egg count.
You need to get PGS ( Preimplantation Genetic Screening ) of the embryos done to assess quality of embryo and the genetic composition of embryo which will give an idea as to why the previous IVF failed.
Let me know if you need anymore help.
Regards
PGS is a better option
Detailed Answer:
Hi,
I understand your concerns about low egg reserve.
The damage is not due to excess testosterone.
You seem to have low egg reserve for your age which is seen in many women.
It is not possible to reverse this aging effect or improve the egg count.
You need to get PGS ( Preimplantation Genetic Screening ) of the embryos done to assess quality of embryo and the genetic composition of embryo which will give an idea as to why the previous IVF failed.
Let me know if you need anymore help.
Regards
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
I do not any genetic conditions to go for PGS. I good hormone levels and could be highly fertile but had low reserve and as a single female used donor sperm. I did not say IVF failed, though short IVF increased uneuploidy rate. The damage is due to excessive testosterone doctors keep on prescribing me as I was told there is a debate on which whether male or female hormones contribute more to fertility. I was hoping to hear how to use estrogen priming therapies with say provynova or estrogen patches or levels of testestorone naturally. Also how to reverse the damage done by imbalanced pill Norimin 1 with double the amount of testosterone on it - I took it for 2 months and it made my cycle length went from 27-30 days to 23-21 days I am horrifies. Please help.
Brief Answer:
Low reserve is age related and not male hormones
Detailed Answer:
Hi,
As per literature and experience it is known that rate of aneuploidy increases with age. Incidence of chromosomal abnormality is high in low egg reserve patients as well as age of around 35 years.
There is debate about use of male hormones but that is unlikely to have resulted in such low reserve. Estrogen patches / estradiol tablets like progynova are not going to help you especially when you have low reserve.
Norimin and testosterone taken for 2 to 3 months would not have caused damage to ovarian reserve and your worry is not justified in this scenario.
Your cycle length variation is related to decreasing egg reserve.
My advice still remains as PGS.
Let me know if you need anymore help.
Regards
Low reserve is age related and not male hormones
Detailed Answer:
Hi,
As per literature and experience it is known that rate of aneuploidy increases with age. Incidence of chromosomal abnormality is high in low egg reserve patients as well as age of around 35 years.
There is debate about use of male hormones but that is unlikely to have resulted in such low reserve. Estrogen patches / estradiol tablets like progynova are not going to help you especially when you have low reserve.
Norimin and testosterone taken for 2 to 3 months would not have caused damage to ovarian reserve and your worry is not justified in this scenario.
Your cycle length variation is related to decreasing egg reserve.
My advice still remains as PGS.
Let me know if you need anymore help.
Regards
Note: Revert back with your gynae reports to get a clear medical analysis by our expert Gynecologic Oncologist. Click here.
Above answer was peer-reviewed by :
Dr. Raju A.T
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