Hello,

Thanks for the question.

First of all I don't completely agree with diagnosis of inflammation of bone. Secondly I think your mother's case has not been completely evaluated.

Her symptoms are suggestive of pedal edema. Retention of water in the soft tissue is the cause of such swelling.This kind of swelling is not specific for one particular cause and can be seen in various conditions. Few such conditions are venous insufficiency in leg, diseases of heart ,kidney .liver,lung etc, lymphedema, hypertension,allergies,anemia, endocrine disorder and hypoproteinemia .From reports only causes related to kidney seems to have been ruled out.Even her thyroid issues might be contributing to leg swelling.

Ideal next step would be to get investigations for other causes.Investigations which can be suggested are lower limb color Doppler,liver function test, 2 decho, hemogram, hormone levels(if needed) and serum protein levels etc.

Usually diagnosis is reached with help of detailed medical history , clinical examination and few investigations.

So I would suggest you to have discussion with your doctor and get investigations done. The treatment is usually directed towards the underlying cause.

Please ask if you want me to explain anything.

Regards.

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