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Does Sertraline Interact With Hydrochlorothiazide?

Posted on Fri, 8 Jul 2016

Question: Hi,
I am a 45 year old woman, I have recently been put on hydrochlorothiazide for my blood pressure. My questions are - 1) Does this have any interaction problem with armour thyroid (I take 60 mg/day when i wake up)? 2) Is there any alcohol interaction that I need to be aware of and what is it? Does it lessen the effectiveness or have another type of interaction? 3) I have also been prescribed Setraline, but have not started taking it. Does Sertraline have any type of interaction with hydrochlorothiazide and can it be taken with alcohol? Lastly I am uploading a copy of my recent lab results. Do you see anything that sticks out to you or should be a cause of concern - specifically with the CMP panel / liver and kidney tests? And what does a low creatnine level mean? Thanks in advance. XXXXX

Answered by Dr. Anshul Varshney (59 minutes later)

Brief Answer:
Avoid alcohol.

Detailed Answer:
Welcome To HCM. I am Dr Anshul Varshney. I can understand your concern.

First of all your reports are good except your blood cholesterol is high and that required attention in form of regular exercises and low caloric diet.

I would say here that Hydrochlorothiazide is absolutely safe with thyroxine as well as Sertaline.

However it might be a problem in case of consuming alcohol altogether. The reason being that this drug in itself is a diuretic and alcohol also acts like a diuretic so excessive diuresis can cause dehydration and sodium , potassium imbalances. So, Alcohol you should limit to very occasional status.

I hope it helps you.
If you have any further query, please ask me.

Above answer was peer-reviewed by : Dr. Arnab Banerjee

Follow up: Dr. Anshul Varshney (25 minutes later)

Hello Doctor,

Thank you for your quick response.
Is armour thyroxine? And does the 0.58 mg / dL for creatnine which is a little below the reference range on the lab sheet mean anything?

Thanks,

XXXXX

Answered by Dr. Anshul Varshney (12 hours later)

Brief Answer:
Yes that's Thyroid.

Detailed Answer:
Hi, Armour thyroid is also a type of thyroxine hormone.
You can continue it if it has been prescribed by your doctor.
This serum creatinine on lower side doesn't have any significance in your case.
If you have any further query, please ask me.

Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Sonia Raina