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Diabetic And Suffers From Arthritis. Treated With Oxygen For Low RBC. Is It Due To Methotrexate?

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Posted on Mon, 1 Jul 2013
Question: Hi my wife is a diabetic and also suffers from arthritis amongst other complaints. She is at present in hospital and being treated with oxygen as she has a very low red cell blood count. without the oxygen she becomes very weak and collapses my daughter and myself think she has damaged her capacity to produce red blood cells through taking Methotrexate .Can this (if this if it the problem causing her to fall ) be corrected and how?
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Answered by Dr. Michelle Gibson James (39 minutes later)
HI, thanks for using healthcare magic

You and your daughter are correct in believing that it might be possible that the methotrexate may have contributed to her anemia.

One of the potential side effects of methotrexate is suppression of the bone marrow where red blood cells as wells as platelets and white cells, are produced.

In this case, there would most likely be a decrease in her white cell and platelet count as well.

If the anemia is related to the methotrexate then your mother may benefit from a medication called leucovorin. This is given to help persons experiencing harmful effects from methotrexate. It is similar to folic acid and helps the body to rebuild new cells.

I hope this helps, feel free to ask any other questions
Note: For further queries, consult a joint and bone specialist, an Orthopaedic surgeon. Book a Call now.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Michelle Gibson James

General & Family Physician

Practicing since :2001

Answered : 16808 Questions

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Diabetic And Suffers From Arthritis. Treated With Oxygen For Low RBC. Is It Due To Methotrexate?

HI, thanks for using healthcare magic

You and your daughter are correct in believing that it might be possible that the methotrexate may have contributed to her anemia.

One of the potential side effects of methotrexate is suppression of the bone marrow where red blood cells as wells as platelets and white cells, are produced.

In this case, there would most likely be a decrease in her white cell and platelet count as well.

If the anemia is related to the methotrexate then your mother may benefit from a medication called leucovorin. This is given to help persons experiencing harmful effects from methotrexate. It is similar to folic acid and helps the body to rebuild new cells.

I hope this helps, feel free to ask any other questions