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Could I Take Amitriptyline Hcl Along With Buspirone Hcl?

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Posted on Thu, 21 Nov 2013
Question: Can amitriptyline hcl and buspirone hcl be taken togther?
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Answered by Dr. Anjana Rao Kavoor (54 minutes later)
Brief Answer: Amitriptyline and buspirone can be taken together Detailed Answer: Hi, Thanks for writing in to us. I have read through your query in detail. In a study in normal volunteers, no interaction of buspirone with amitriptyline was seen. After addition of buspirone to the amitriptyline dose regimen, no statistically significant differences in the steady-state pharmacokinetic parameters (Cmax, AUC, and Cmin) of amitriptyline or its metabolite nortriptyline were observed. This is from the official FDA information release. Hope your query is answered. Do write back in case of doubts. Dr.A.Rao Kavoor
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Dr. Anjana Rao Kavoor

Psychiatrist

Practicing since :2008

Answered : 1197 Questions

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Could I Take Amitriptyline Hcl Along With Buspirone Hcl?

Brief Answer: Amitriptyline and buspirone can be taken together Detailed Answer: Hi, Thanks for writing in to us. I have read through your query in detail. In a study in normal volunteers, no interaction of buspirone with amitriptyline was seen. After addition of buspirone to the amitriptyline dose regimen, no statistically significant differences in the steady-state pharmacokinetic parameters (Cmax, AUC, and Cmin) of amitriptyline or its metabolite nortriptyline were observed. This is from the official FDA information release. Hope your query is answered. Do write back in case of doubts. Dr.A.Rao Kavoor