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Can Amoxicillin And Excedrin Be Taken Together?
Question: I have just started taking Amoxicillin Pot Clavulanate for possible pneumonia.
With a headache, can I simultaneously use some Excedrin?
With a headache, can I simultaneously use some Excedrin?
Brief Answer:
Discussion follows
Detailed Answer:
Hello,
Welcome and thanks for your query.
Yes , but take Excedrin aspirin free. Aspirin , present in Excedrin Extra Strength has an interaction with Amoxicillin and they raise the blood level of each other.
Do get back to me if you have further queries
Discussion follows
Detailed Answer:
Hello,
Welcome and thanks for your query.
Yes , but take Excedrin aspirin free. Aspirin , present in Excedrin Extra Strength has an interaction with Amoxicillin and they raise the blood level of each other.
Do get back to me if you have further queries
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
What does it mean that they raise the blood level of each other?
What problem might that cause?
Thank you.
What problem might that cause?
Thank you.
Brief Answer:
Welcome
Detailed Answer:
The blood levels of aspirin and amoxicillin increase by two mechanisms.
1. They both compete for plasma protein binding. So the amount of free medicines in the blood increase.
2. Each decrease the excretion of the other through the kidneys, again leading to accumulation of the medicines in the blood.
Normally we try to avoid medicines that interact in such ways if possible.
Both Amoxicillin and aspirin have a fairly wide margin of safety, so at low doses of these medicines, there may not be any serious side effect but at higher doses, this effect would be like an over dose.
So caution is advised.
Wish you a quick recovery.
Welcome
Detailed Answer:
The blood levels of aspirin and amoxicillin increase by two mechanisms.
1. They both compete for plasma protein binding. So the amount of free medicines in the blood increase.
2. Each decrease the excretion of the other through the kidneys, again leading to accumulation of the medicines in the blood.
Normally we try to avoid medicines that interact in such ways if possible.
Both Amoxicillin and aspirin have a fairly wide margin of safety, so at low doses of these medicines, there may not be any serious side effect but at higher doses, this effect would be like an over dose.
So caution is advised.
Wish you a quick recovery.
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
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