i am a high factor 8. my hematoligist is having a hard time regulating my d-dimer. i found out about two months ago, after going through some old papers of my mother's that mayo clinic diagnosed her with ms in january of 1963 . my father never told me about this. i stared having severe joint pain and reacuring outbreaks of hives . in 2004 i developed a severe headache and was found to have a large blood clot in my brain. i also had blood clot in each lung after back surgery in 2011. now that i know my mother was found to have ms , could this be what i have been dealing with since age 41?