Hi.... Peripheral tolerance refers to the tolerance on the functions of the T cell and B cell. T cell and B cell are the immunity cells in the human body. They deliver this funtion by different mechanism. It is activated by the presence of receptors on the cells usually refered to as MHC. The target cells for the MHC is the antigen (anything that is an not part of the body). There are instances when the MHC reacts angainst the own body resulting in the develpment of autoimmunity state or disease. The mechanism where in the develpopment of such autoimnunity is prevented is refered to as development of tolerance. It can happen either at the central level i.e at the stage of the production or at the peripheral level i.e at the stage of its release.
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my mom was diagnosed with interstitial lung disease one and half yr back and has been on steroids since then.four mnths back she developed pulmonary TB.she could not tolerate the standard ATT,so she is taking isoniazid,ethambutol and levofloxacin.but for past one mnth she developed peripheral nuropathy.nerve conduction test showed reduced amplitutude in cp and pt nerves.the doc has stoped isoniazid for one week.what wud b the further management of her disease?
hi my name is kevin , I am failing peripheral vision test and I cant understand it . I had a small stroke ,my right eye was affected . it has improved I would think 90 per cent.i can read perfectly now which I couldnt ,I never bumped into any thing or people even at night ,played golf 2 weeks after stroke, no problems , one doctor passed for driving said I was within the recommended criteria. on my next visit I was failed by a more senior doctor. after being passed firstly I drove for6 weeks with no problems . iam not disputing the test results I just cant relate what I can see to what she can see on readout.i am 73 and am extremely happy with my recovery. can see both sides of the street, junctions. while looking straight while not turning my head. frustrated .can you understand. thanks
DEAR DOCTOR,I AM SUFFERING FROM PERIPHERAL NEUROPATHY DUE TO EXCESSIVE USE OF ALCOHOL, ALSO MY MOTHER WAS SUFFERING FROM NEUROPATHY DUE TO WEAKNESS OR SOMETHING LIKE THAT. I AM USING PREGABID FORTE 75 - DAILY ONE TABLET, BUT IT GIVES ME A VERY VERY VERY MEAGRE RELIEF, PLEASE DIAGNOSE ME...