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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does The Following MRI Scan Of The Brain Indicate?

My 9 month old daughter MRI scan showed following: The high frontal subcortical white matter superior and middle frontal gyri shows T2 hyperintense signal suppressed on FLAIR suggestive of gliosis(R L). Structural anatomy and parenchymal signal pattern of remaining brain are normal in brain stem, cerebellum and both cereberal hemisphere. Focal structural lesions, diffusion restriction, edema and mass effect are absent in brain. Ventricular system of brain has normal size and configuration. CSF cisterns at base of brain, around mid-brain and over cerebellar and cereberal surface are clear. Cranial nerve segments in cerebello-pointe angles are normal bilaterally. Major intracranial arteries have normal course, calibre and flow-voids. Petrous temporal bones have normal symmetry. Sella and juxta sellar regions are normal. Orbits and their contents reveal normal anatomy. Impression: MRI head scan reveals Mild gliotic changes in high frontal subcortical white matter bilaterally, prominent on right side. My daughter was not giving social smile till 6 months and hence we were worried. She has started smiling now from 8 months onwards, but has squint in her eyes. She s 9 month old and have not started crawling or sitting up yet as well. We are worried day and night if there is some issue with her and trying to get all medical check ups done. She had viral fevers and lot of blood in her stool when she was 6 months old. Doctors were not able to diagnose anything and after some medication and a week at hospital, she got better. The latest gliosis has scared us and we are worried if it has impacted her brain and caused any brain damage, which could hinder her growth. I would be extremely grateful if you could shed some light on what could cause gliosis, and whether it has any side effects that we need to take care of, any treatments which we can start at early stage so that her growth is normal and she doesn t get any impairments.
Wed, 3 Jun 2015
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Radiologist 's  Response
Hello

Gliosis is reparative mechanism in brain in response to injury.Injury may be due to ischemia,infection etc.
Small gliosis in your daughter's case may be due to perinatal ischemia.Gliosis is due to proliferation of glial cells in brain.
It is a healed stage and this specific finding doesn't require any treatment.
Your daughter may need supportive management only.
She need to be properly examined by a neurologist.

Get well soon.
Take Care
Dr.Indu Bhushan
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What Does The Following MRI Scan Of The Brain Indicate?

Hello Gliosis is reparative mechanism in brain in response to injury.Injury may be due to ischemia,infection etc. Small gliosis in your daughter s case may be due to perinatal ischemia.Gliosis is due to proliferation of glial cells in brain. It is a healed stage and this specific finding doesn t require any treatment. Your daughter may need supportive management only. She need to be properly examined by a neurologist. Get well soon. Take Care Dr.Indu Bhushan