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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does CA125 Of 127 After Surgery For Cancer Suggest?

Thank you. My wife has Stage 3C, had successful debulking and a post op CA 125 of 64. She was hesitant about chemo. Went to health clinic to change diet to vegan. 2nd week @ clinic she felt the cancer growing again. Now approx 8 weeks post surgery & CA125 is at 127, CT without enhancement shows more growth. PET scheduled for tomorrow. Chemo to begin July 1. What should we expect?
Wed, 24 Dec 2014
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Pulmonologist 's  Response
Thanks for your question on HCM.
Postoperative chemotherapy is adviced to prevent local as well as distal spread.
During surgery, due to handling of tumour mass, possibility of spillage is high. And this is the reason for local recurrence. So post operatively chemotherapy is given.
Since your wife has not taken post operative chemotherapy with increasing CA 125, growth on plain CT, all these suggest local recurrence.
So get done PET SCAN to rule out local as well as distal spread.
And chemotherapy is the only option now.
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What Does CA125 Of 127 After Surgery For Cancer Suggest?

Thanks for your question on HCM. Postoperative chemotherapy is adviced to prevent local as well as distal spread. During surgery, due to handling of tumour mass, possibility of spillage is high. And this is the reason for local recurrence. So post operatively chemotherapy is given. Since your wife has not taken post operative chemotherapy with increasing CA 125, growth on plain CT, all these suggest local recurrence. So get done PET SCAN to rule out local as well as distal spread. And chemotherapy is the only option now.