My sister has been having lower leg pain and weakness for at least 2 months now and it is getting more painful and med like Aleve or Advil bring no relief. She has severe sleep apnea and does not use her CPAP, sleeps in short intervals but can t sleep more than 4 hours max, and she is on several high dose medications (Lithium, Ability, Lomotrigine,) for manic depression, along with Lipitor for Cholesterol and two different high blood pressure prescriptions, and Modafinil 200mg twice a day. She often has some chest pain as well, which could be stress related, but I am concerned that there may be some contradiction going on with the drugs.