Hello! Thanks for using healthcaremagic.com I read carefully your question and understand your concern. I think you have angioedema. Patients from my clinic who presents this symptoms is caused most of the time by some alergic reaction to a food they didnt know they were alergic. Antihistamines block the effects of histamine, so they help stop itching and reduce the swelling around the lips. Examples of antihistamines include: Cetirizine Fexofenadine Loratadine In most people, modern antihistamines do not cause drowsiness, although there are some exceptions.