Yes my friend ,male ,47, has had a two very worrisome incidents over the last 6_8 myths. The first time he took some male enhancements pills and he got pretty sick with them and he said he had very loud like popping inside his head with pain also. This next time happened just a day or two ago he was in his deer stand. He had not taken the male enhancements since then so he is not sure what brought it in this time but the same thing very loud hurtful (like popping.