I am currently taking NORVASC 5mg. 2x daily, aspirin 81 mg. 1 x daily, atorvastation (Lipitor) 40 mg. 1 x daily, and Ticagrelor (Brilinta) 2 x daily. the ones I take 2 x daily ,I take 1 in the morning at 8 a,m. and one at 8p.m. the ones I take 1 x daily I take at 8 p.m. that s a total of 2 pills in the morning and 4 at night. will all these medicines cause me to feel fatigue and run down