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What Causes Severe Fatigue While On Diltiazem And Tamsulosin?
My father has been getting more lethargic. He b/p was 95/57. This has been going on for several days.He is on Diltiazen HCL, enalapril, tamsulosin HCL..Should he hold one of these for a day to see if his b/p goes back up. It's the holiday and we will be contacting his FD on Monday?
Tue, 24 Jan 2017
Hi & Welcome.
It is due to hypotension caused by drug to drug interactions.
Diltiazem is a calcium channel blocker and Enalapril is an angiotensin converting enzyme inhibitor. These drugs are commonly used to treat high BP.
Tamsulosin is a selective alfa1 receptor blocker mainly used in the treatment of benign prostatic enlargement and also for high BP.
Diltiazem when taken along with Tamsulosin may increase the blood levels and effects of Tamsulosin. This can cause BP to fall excessively and heart rate to increase, especially while standing from a sitting or lying position.
The risk of other side effects such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitations, and priapism may also increase.
He may need a dose adjustment or to stop taking Tamsulosin till you consult his FD.
Hope this will help your father to get relief.
It is due to hypotension caused by drug to drug interactions.
Diltiazem is a calcium channel blocker and Enalapril is an angiotensin converting enzyme inhibitor. These drugs are commonly used to treat high BP.
Tamsulosin is a selective alfa1 receptor blocker mainly used in the treatment of benign prostatic enlargement and also for high BP.
Diltiazem when taken along with Tamsulosin may increase the blood levels and effects of Tamsulosin. This can cause BP to fall excessively and heart rate to increase, especially while standing from a sitting or lying position.
The risk of other side effects such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitations, and priapism may also increase.
He may need a dose adjustment or to stop taking Tamsulosin till you consult his FD.
Hope this will help your father to get relief.
I find this answer helpful
Hi & Welcome.
This seems to due to hypotension (low BP) caused by harmful drug interaction.
Diltiazem when taken along with Tamsulosin will increase its blood levels and effects of Tamsulosin. This can cause BP to fall excessively and heart rate to increase, especially while standing from a sitting or lying position.
The risk of other side effects such as dizziness, lightheadedness, severe fatigue, fainting, headache, flushing, nasal congestion and palpitations may also increase.
So, he needs to discontinue taking Tamsulosin till you consult his FD and his BP needs to be monitored.
Hope the advice given above would be useful.
This seems to due to hypotension (low BP) caused by harmful drug interaction.
Diltiazem when taken along with Tamsulosin will increase its blood levels and effects of Tamsulosin. This can cause BP to fall excessively and heart rate to increase, especially while standing from a sitting or lying position.
The risk of other side effects such as dizziness, lightheadedness, severe fatigue, fainting, headache, flushing, nasal congestion and palpitations may also increase.
So, he needs to discontinue taking Tamsulosin till you consult his FD and his BP needs to be monitored.
Hope the advice given above would be useful.
I find this answer helpful
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