I accidentally overdosed myself with estrace three weeks ago! The dosage that was subscribe was 1 gram twice a day and I use the whole applicator twice a day which consist of 4 grams. I was given Estrace as a preventative for vaginal driness. I am experiencing like needle pricks all over my body from my hands to my legs my neck. I am feeling like inner burning sensations. My mouth is constantly dry. I can t drink enough water to quinch my thirst. My head constantly hurt. My shoulders, back aches from pricks and I feel as I am under water water. My skin is constantly crawling. Do I need to see a doctor.