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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What causes blisters on hands?

Small areas appear below the surface of the skin on both hands. The areas are about the 1/8” to ¼” in size not necessarily round. They seem to be like blisters below the skin. They do not hurt unless pressure is applied like with a fingernail. The discoloration which again appears to be below the surface of the skin almost appears transparent almost like tapioca. The areas appear mostly on the sides of the fingers. The areas feel somewhat hard or firm when touched. After 2-3 weeks some of the areas start to come to the surface and the skin over them begins to dry out and flake off. Not all of them do this. Some just disappear after a few weeks. These seem to have lasted about 4-5 weeks and then disappeared as mysteriously as they appeared. I think they might have been caused by something like Herpes simplex which causes fever blisters or possibly warts. Some research suggests it might be Pompholyx Eczema. However, from what I have learned about this there is usually some rash or itching associated with it. I do not have any of that. Some of the areas exhibit Umbilication (formation of a depression at the top of a papule, vesicle, or pustule) and Induration (dermal thickening causing the cutaneous surface to feel thicker and firmer). Could It could possibly be one of the following: Papule – a circumscribed, solid elevation of skin with no visible fluid Nodule – morphologically similar to a papule, and most frequently centered in the dermis or subcutaneous fat. I included these because they somewhat describe the symptoms.
Thu, 29 Jun 2017
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Dermatologist 's  Response
hi,
thank you for putting up your query on HCM.
mam, as per your history of lesions, I can make out, you have pompholyx eczema.
This is characterized by tense, deep-seated crops of "sago-like" vesicles on palms, and/or palmar aspect and sides of the fingers with recurrences. The lesions are pruritic as such, but no history of pruritus can be possible. Irritants like soluble oils can also cause pompholyx.
Long hours of wet work, low humidity, and hard water increase the risk for dermatitis.
these can be treated by using potent topical corticosteroids in the form of betamethasone valerate(0.1%) cream applied twice daily for 4 weeks and then once a day for 2-3 wks and proper mosturization and hydration of skin by Using white soft paraffin twice a day and olive oil or coconut oil once a day.
thank you
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What causes blisters on hands?

hi, thank you for putting up your query on HCM. mam, as per your history of lesions, I can make out, you have pompholyx eczema. This is characterized by tense, deep-seated crops of sago-like vesicles on palms, and/or palmar aspect and sides of the fingers with recurrences. The lesions are pruritic as such, but no history of pruritus can be possible. Irritants like soluble oils can also cause pompholyx. Long hours of wet work, low humidity, and hard water increase the risk for dermatitis. these can be treated by using potent topical corticosteroids in the form of betamethasone valerate(0.1%) cream applied twice daily for 4 weeks and then once a day for 2-3 wks and proper mosturization and hydration of skin by Using white soft paraffin twice a day and olive oil or coconut oil once a day. thank you