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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes An Increase In Crp Level?

Hi, my sister got a new baby girl, she is 8 days old today. 2 hours after born, he had high CRP lever (doctor say 7 mg/L and normal lever for baby is 5 mg/L). Then she placed on perinatology room, they took some tests, and then doctors started antibiotics. 1st antibiotics given to her is MIKASIN . 3 days later, her CRP level increase to 11 mg/L . then they replace the antobiotik to be TAXEGRAM but 2 days later her CRP level increase to 20 mg/L. When she was born. Doctor has took some test but there is no source found that why CRP level is high. Can you please help? Thank you and warm regards.
Wed, 10 Sep 2014
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General & Family Physician 's  Response
Thank you for posting on HCM
CRP level is indication of marker of underlying infection / inflammation.
In newborn babies high CRP level needs investigations - septic screen & doctor has correctly started antibiotics empirically pending test results.
Ideally the antibiotics baby has been given would help to bring down level of CRP fairly soon - but as they are still rising - additional tests - blood culture, Xray, urine & lumbar fluid aspiration will need to be performed.
All the best wishes
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What Causes An Increase In Crp Level?

Thank you for posting on HCM CRP level is indication of marker of underlying infection / inflammation. In newborn babies high CRP level needs investigations - septic screen & doctor has correctly started antibiotics empirically pending test results. Ideally the antibiotics baby has been given would help to bring down level of CRP fairly soon - but as they are still rising - additional tests - blood culture, Xray, urine & lumbar fluid aspiration will need to be performed. All the best wishes