Hello dear Greetings Regarding your experience with abdominal pain that wax and wean following intake of proton pump inhibitors I am suggesting that you have developed a peptic ulcer disease In view of this please do an endoscopy to rule out this condition Meanwhile please see a gastroenterologist specialist with the result and for further clinical assessment and adequate drug prescription Concerning your tightness at your right chest with radiating pain to the shoulder and neck I will suggest the following differential diagnosis Angina pectoris Myocardial ischaemia Coronary vasospasm Costochondritis Acute chest syndrome Please do the following test Chest x-ray ECG EKG Coronary angiography Meanwhile please see a cardiologist specialist with the results and for expect management Moreover please take some analgesic pending your appointment I hope this helps Regards