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Dr. Andrew Rynne
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What are the side effects of Prolia injection?

Thank You Doc, I have been advised by my doctor that he wants me to have a Prolia injection. I have been reading the reviews of the side effects and are not too keen on having it. I am 83yrs of age with very bad back and hip problems. Would a hip replacement do the job.? Ann
Mon, 23 Mar 2015
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General & Family Physician 's  Response
Dear Patient,

the prolia injection will have some stabilizing effect on your bone mass, i am assuming the bone mass got detected through special x ray (osteodensitometry) examination and the result showed that it is to low for your age group.

The following serious adverse reactions are discussed:

Hypocalcemia (low blood calcium)
Osteonecrosis of the Jaw
Atypical Subtrochanteric and Diaphyseal Femoral Fractures
Dermatologic Reactions

Other possible side effects with Prolia in patients with postmenopausal osteoporosis are musculoskeletal pain, hypercholesterolemia, back pain, pain in extremity, and cystitis.
Also back pain and constipation can occur.

However, it is still advisable you give it a try since low bone mass can also lead to a lot of dangerous conditions like spine and femoral fractures.
It is also important you take in enough calcium and vitamin D (ask your dotor about that). Hope this is helping you , if you have any clarificatons you can get back to me, if this was helpful please kindly rate my answer. Best regards
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