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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Are The Harmful Effects Of C. Difficile Colitis On Body?

My question is will c difcolitis damage other parts of the body cause ive had this for over a yr now real bad my doctor has tryed several rounds of flagyl and 2 rounds of vancomycin tht didnt work either so just the other day we tryed FMT it seemed to work at first but now i think its back idk what to do now i have no energy at all when i walk the pain in my gut gets worse sumtimes its hard to breathe.i can go on about but question is will it damage my other organs? I would appreciate very much if u could give sum answers thank u
Fri, 5 Jun 2020
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General & Family Physician,  's  Response
Hi.
I've gone through your query and I can understand your anxiety.

Clostridium difficile infections either subsides within few weeks of starting antibiotic treatment or few cases will become carriers with diarrhea, severe colitis and may have multiple relapses.

So repeated infection not only affects the colon but also other systems like blood, kidney, liver resulting in shock & death.

However, higher rates of reinfection & recurrence is documented with in few weeks to months of stopping the antibiotics, which demands additional therapy.

Best treatment for relapses would be,

1.Repeated dose of either oral metronidazole or vancomycin for 10–14 days. But successful in only 50% of patients.

2. Fecal microbiota transplantation (FMT) can be tried in patients with more recurrences & failure antibiotic treatment. It has 80%-90% success rate.

3. Probiotics (yogurt, other fermented foods etc) intake will help in the growth of good gut bacteria & minimise the risk of reinfection with C diff.

Hope I have answered your query. Let me know if I can assist you further. Take care.

Regards,
Dr. Yogapriya V, General and family physician.
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What Are The Harmful Effects Of C. Difficile Colitis On Body?

Hi. I ve gone through your query and I can understand your anxiety. Clostridium difficile infections either subsides within few weeks of starting antibiotic treatment or few cases will become carriers with diarrhea, severe colitis and may have multiple relapses. So repeated infection not only affects the colon but also other systems like blood, kidney, liver resulting in shock & death. However, higher rates of reinfection & recurrence is documented with in few weeks to months of stopping the antibiotics, which demands additional therapy. Best treatment for relapses would be, 1.Repeated dose of either oral metronidazole or vancomycin for 10–14 days. But successful in only 50% of patients. 2. Fecal microbiota transplantation (FMT) can be tried in patients with more recurrences & failure antibiotic treatment. It has 80%-90% success rate. 3. Probiotics (yogurt, other fermented foods etc) intake will help in the growth of good gut bacteria & minimise the risk of reinfection with C diff. Hope I have answered your query. Let me know if I can assist you further. Take care. Regards, Dr. Yogapriya V, General and family physician.