Hello I really appreciate your concern for your mother Here, I would like more details like her blood reports of hemoglobin and CBC If possible upload a photograph of the ankle Her relevant medical history like diabetes or other metabolic disease Swelling in ankle with history of arthritis might be related to inflammation of the joint or fracture since she is a post menopausal lady and there are chances of post menopausal osteoporosis and fracture due to trivial trauma. I would advise you to follow these guidelines Keep her leg elevated by placing pillow underneath the ankle You can give her tab chymoral forte 2 tablets half an hour before food She should take multivitamins and calcium supplements Ankle brace or crepe bandage can be used to maintain immobilisation and stability of the joint Ask her to take complete best rest until diagnosis confirms. Hope this answers your question Please feel free to ask for follow up question I will.be happy to help you Best wishes