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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is Multiple Sclerosis In Twins Be Hereditary?

If someone argued that the reason twins often share multiple sclerosis is not because it’s hereditary, but because of some abnormality in the mother’s pregnancy such as maternal exposure to a toxin or virus. How would i argue against this hypothesis?
Wed, 31 May 2017
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Pediatrician 's  Response
hi,
A combination of genetics and environmental factors appears to be responsible for mult
variations in dozens of genes are thought to be involved in multiple sclerosis risk. Changes in the HLA-DRB1 gene are the strongest genetic risk factors for developing multiple sclerosis.
Other factors associated with an increased risk of developing multiple sclerosis include changes in the IL7R gene .
environmental factors are such as exposure to the Epstein-Barr virus, low levels of vitamin D, and smoking.

w
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Note: For detailed guidance on genetic screening consult a genetics specialist
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Is Multiple Sclerosis In Twins Be Hereditary?

hi, A combination of genetics and environmental factors appears to be responsible for mult variations in dozens of genes are thought to be involved in multiple sclerosis risk. Changes in the HLA-DRB1 gene are the strongest genetic risk factors for developing multiple sclerosis. Other factors associated with an increased risk of developing multiple sclerosis include changes in the IL7R gene . environmental factors are such as exposure to the Epstein-Barr virus, low levels of vitamin D, and smoking. w