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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is Linzess Safe To Take At Night?

I have been plaqued with IBS-C my entire life. The past three months I have been using Linzess 145mg. A game changer, however it wasn t working every day. Dr. raised doseage to 290 a few days ago. My question is can I take this med at night? Reason being, sometimes it works just before I have to leave for work which is a one hour commute...not good. Or would it be best that I set alarm for 3 in the morning to take and then go back to sleep?
Sat, 30 Mar 2019
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General & Family Physician 's  Response
Dosage Forms & Strengths of linzess

capsule are

72mcg
145mcg
290mcg

Irritable Bowel Syndrome

Indicated in adults for irritable bowel syndrome with constipation

290 mcg PO qDay on empty stomach; administer at least 30 minutes before first meal of the day
Chronic Idiopathic Constipation

Indicated for adults with chronic idiopathic constipation

Recommended dose: 145 mcg PO qDay

72 mcg PO qDay may be used based on individual presentation

Take on an empty stomach; administer at least 30 minutes before first meal of the day.....
so it will be best that you set alarm for 3 in the morning to take and then go back to sleep as it is to be taken empty stomach
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Is Linzess Safe To Take At Night?

Dosage Forms & Strengths of linzess capsule are 72mcg 145mcg 290mcg Irritable Bowel Syndrome Indicated in adults for irritable bowel syndrome with constipation 290 mcg PO qDay on empty stomach; administer at least 30 minutes before first meal of the day Chronic Idiopathic Constipation Indicated for adults with chronic idiopathic constipation Recommended dose: 145 mcg PO qDay 72 mcg PO qDay may be used based on individual presentation Take on an empty stomach; administer at least 30 minutes before first meal of the day..... so it will be best that you set alarm for 3 in the morning to take and then go back to sleep as it is to be taken empty stomach