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Dr. Andrew Rynne

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Is Duloxetine Safe Instead Of Gralise For Nephropathy In The Foot?

I am currently taking Gralise 1800 mg nightly before bed to help with Neuropathy in my foot caused by nerve damage from an injury. My new doctor wants to switch me to Duloxentine 30mg. I have read the side effects and am a little anxious to start it. I am to take this along with my Gralise until this has time to get into my system(1 month). Should I take this at night along with the Gralise? It just says to take once a day
Tue, 6 Jun 2017
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Orthopaedic Surgeon 's  Response
Hello and Welcome to ‘Ask A Doctor’ service.
I have reviewed your query and here is my advice.

The interaction risk of these 2 drugs is moderate that means not high but also not low. If you take these 2 drugs at the same time then you have increased risk of side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. In order to decrease the chance of these side effects, I suggest you take the pills at different times.

Hope I have answered your query. Let me know if I can assist you further.

Regards,
Dr. Edvin Selmani
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Is Duloxetine Safe Instead Of Gralise For Nephropathy In The Foot?

Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. The interaction risk of these 2 drugs is moderate that means not high but also not low. If you take these 2 drugs at the same time then you have increased risk of side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. In order to decrease the chance of these side effects, I suggest you take the pills at different times. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Edvin Selmani