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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is Beta-sitosterol Effective To Treat Osteo- Arthritis?

Beta-sitosterol I see that it used for reducing inflammation for different maladies how effective is it for , emptying the bladder reducing frequent bathroom visits, the size of prostate emptying the bladder, reduction of cholesterol compared to statins and helping the inflammation in people with osteo- arthritis. Are the claims like so many other supplements all hype or is there any validity. Thank you for an honest response, MJO
Mon, 22 May 2017
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General & Family Physician,  's  Response
Hi,
Thanks for posting in HCM.
I understand your concern.
Here are some of the details about the medication which you have asked for.
beta-sitosterol is one of several phytosterols (sterols from plant origin) with chemical structures similar to that of cholesterol.
It is shown to have the following effects:
1. cholesterol lowering effects.
2. Immunomodulator action.
3.Anti-inflammatory effects.
Hence, beta-sitosterol is used for heart disease, high cholesterol, preventing colon cancer, gallstones, the common cold and flu (influenza), HIV/AIDS, rheumatoid arthritis, tuberculosis, psoriasis, allergies, cervical cancer, fibromyalgia, systemic lupus erythematosus (SLE), asthma, hair loss, bronchitis, migraine headache and chronic fatigue syndrome.
Some men use beta-sitosterol for enlarged prostate (benign prostatic hyperplasia) and some women use it for symptoms of menopause.
However, more clinical studies are needed to verify the benefits of beta-sitosterol in the conditions which it has been used.
Hope the information provided would be helpful.
All the best.
Regards,
Dr.Ashakiran.S.,
MBBS., MD.
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Is Beta-sitosterol Effective To Treat Osteo- Arthritis?

Hi, Thanks for posting in HCM. I understand your concern. Here are some of the details about the medication which you have asked for. beta-sitosterol is one of several phytosterols (sterols from plant origin) with chemical structures similar to that of cholesterol. It is shown to have the following effects: 1. cholesterol lowering effects. 2. Immunomodulator action. 3.Anti-inflammatory effects. Hence, beta-sitosterol is used for heart disease, high cholesterol, preventing colon cancer, gallstones, the common cold and flu (influenza), HIV/AIDS, rheumatoid arthritis, tuberculosis, psoriasis, allergies, cervical cancer, fibromyalgia, systemic lupus erythematosus (SLE), asthma, hair loss, bronchitis, migraine headache and chronic fatigue syndrome. Some men use beta-sitosterol for enlarged prostate (benign prostatic hyperplasia) and some women use it for symptoms of menopause. However, more clinical studies are needed to verify the benefits of beta-sitosterol in the conditions which it has been used. Hope the information provided would be helpful. All the best. Regards, Dr.Ashakiran.S., MBBS., MD.