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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is ALT Level Of 82 And GGT Level Of 91 A Cause For Concern?

Is Alt at 82 and GGt at 91 is dangerous because my son takes épival 750 mg in morning and 1000 mg in dinnig for a big epilepsis . His weight is 233 lbs . He also have a DX of autism. Epilepsis is almost on control but what is my option? Continue to control the epilepsis or having a liver dammage?
Mon, 8 Jun 2015
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General & Family Physician,  's  Response
Hi
Welcome to HCM.
I appreciate your concern for your son's health problem.

Since he has been taking Epival, in addition to increased appetite and weight gain, hair loss or discoloration its use is also associated with liver toxicity which is reflected in the form of raised ALT and GGT levels.

Indeed his fits are controlled with twice daily doses of Epival, but continued liver damage could be fatal for him.

So, in view of the harmful liver toxic effects of Epival, he should be re-evaluated by his treating physician/neurologist for an effective alternate drug like Carbamazepine or Phenytoin which are less like to cause liver damage.

Hope the suggestion given above could be beneficial for him.

Best regards.
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Is ALT Level Of 82 And GGT Level Of 91 A Cause For Concern?

Hi Welcome to HCM. I appreciate your concern for your son s health problem. Since he has been taking Epival, in addition to increased appetite and weight gain, hair loss or discoloration its use is also associated with liver toxicity which is reflected in the form of raised ALT and GGT levels. Indeed his fits are controlled with twice daily doses of Epival, but continued liver damage could be fatal for him. So, in view of the harmful liver toxic effects of Epival, he should be re-evaluated by his treating physician/neurologist for an effective alternate drug like Carbamazepine or Phenytoin which are less like to cause liver damage. Hope the suggestion given above could be beneficial for him. Best regards.