I have Hasimoto's, and feel that some of the pain I am experiencing in the lower legs is from that. My doctor does not want to change my thyroid dosage. I also have fluid retention in the legs, and pretty much all over. I have low back pain, also. I am 59, and up until about 9 months ago, was walking 3 miles a day with a steep 25 minute hill. I have done this for years. Now walking is very painful, and just do what I have to at work. Any ideas? I started taking proteolytic enzymes, and it helped a few months ago, but not now.