Hi,I am Dr. Shanthi.E (General & Family Physician). I will be looking into your question and guiding you through the process. Please write your question below.
I am trying to put into easy to understand terms the following information PHARMACOKINETICS Absorption: Rapid and complete. Absolute bioavailability (50%); Tmax=2 hrs. Distribution: Plasma protein binding (approx 85%); may be found in breast milk. Metabolism: Extensive; demethylation and hydroxylation via CYP2D6, CYP1A2, and CYP3A followed by glucuronide conjugation. Elimination: Urine (75%), feces (15%); T1/2=approx 20-40 hrs.
Thu, 1 Oct 2015
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