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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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I Am Trying To Put Into Easy To Understand Terms

I am trying to put into easy to understand terms the following information
PHARMACOKINETICS
Absorption: Rapid and complete. Absolute bioavailability (50%); Tmax=2 hrs. Distribution: Plasma protein binding (approx 85%); may be found in breast milk. Metabolism: Extensive; demethylation and hydroxylation via CYP2D6, CYP1A2, and CYP3A followed by glucuronide conjugation. Elimination: Urine (75%), feces (15%); T1/2=approx 20-40 hrs.




Thu, 1 Oct 2015
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I Am Trying To Put Into Easy To Understand Terms