I am a 43 yr old female with MS and Cranial Vasculitous. 3 days ago felt very sharp pain in back of left calf. There is a bulging vein running from just below bend of knee about 2-4 inches down. No redness. No swelling. Just severe pain. I take 2-81mg asprin daily, 30mg Morphine bid, Vicodin 10/325 - 5 x's daily for MS pain, plus Tecfidera, Zonisaminde, Nudexta, Baclofen, Klonopin, Lipator, Cymbalta, and Vit D3 and B12. Ideas?