Hi.. Welcome to HEALTHCARE MAGIC.. I have gone through your query and can understand your concerns.. As per your complain it seems in case f you have treatment failed for exfoliative Chelitis you can start using Tacrolimus ointment and marigold ointment as they are found useful on researches.. Do cool compresses over lips and apply thick coat of Petroleum jelly and beeswax containing lip balm.. Keep well hydrated.. Avoid lip sucking, lip licking and lip biting habit and mouth breathing.. You should also get checked for bacterial infection ( staphylococcus infection) as well as Yeast infection.. Hope this information helps.. Thanks and regards. Dr.Honey Nandwani Arora.