Dear Dr. Rynne, I am a relatively healthy, 47 YO, white male and was recently diagnosed with a genital HSV-1 infection that I acquired from a previous partner that was not aware they were infected. My current partner has tested negative for both HSV-1 and HSV-2 and is being very supportive. My main concern now obviously is keeping her from getting infected. I have several questions surrounding this that I am having a hard time finding answers to. I m hoping you can help. 1) The biggest current issue is that I am afraid to kiss my partner on the lips for fear of giving her an oral HSV-1 infection. It is not clear to me if I can be infected both orally and genitally. I have never had symptoms of an oral infection. Is there any way to tell if I do have oral HSV-1 and, if there is not a way to tell, what are your recommendations for kissing? 2) Although I am sure you will recommend a condom for every act of penetrative sex going forward (even though we dislike the lack of intimacy when using them), I did have several blisters during my outbreak that would definitely NOT be covered by a condom. How should we best proceed in ensuring her safety during vaginal sex? 3) What are the risks / ramifications of her performing oral sex on me and me on her? Seeing as how I acquired HSV-1 from someone with an oral infection, I suppose I am at risk of passing it to her in the same way IF I have the infection in my mouth (see question one). I am also wondering if she is at risk of acquiring an oral HSV-1 infection from giving me unprotected oral sex. 4) Finally, I am in the middle of a course of 400mg Acyclovir TID and am tolerating it fairly well - a little nausea and diarrhea - but nothing I can t manage. Would you recommend me going on daily suppression therapy to help minimise her risk? Thanks for your reply, I really appreciate any advice you can give so that we can get back to as close to normal ASAP.