Hi, I have severe sleep insommia as well as PLMD, have been trying many different meds. Nothing seems to work. Normal sleep pills just make me stoned but do not make me sleep. Have tried the normal meds for RSL/PLMD. I do not have RSL, but an over night stay at the sleep clinic, diagnosed the PLMD. The latest i have been is to take quetiapine 25mg and Clonazepam 25mg at night. I also take a 24 hour/release zytram for DDD, that has made my back old before it's time as due to previous jobs.(Tramadol for breakthrough pain) I rarely take the tramadol and it has never made me sleepy. I have complained about being tired and lack of sleep since I was around 25 ( I am now 58) . Used to be able to handle the tiredness, but it is getting worse. Wondering since the drugs that they are giving me to try, if I should try medical marijuana. I have never been a smoker cigarettes or otherwise, but the drugs I am trying are scary drugs, one is knock out drug, that I have to go online read about then sign that I have read it. Don't like being stoned but sleep would be good and I have such a hangover from some of the other drugs, that really don't do much anyhow. Should also add that I have taken pain management for my back pain, and do imaginering and controlled breathing exercises so I don't have to take as much pain meds. I also keep up with back exercises and do all the sleep hygiene that I have learned about. I have been under the sleep clinic at the Calgary, Alberta for over three years, and my doctors there admit that they are starting to bet stumped. Any ideas? oh yes had the sleep apenea machine for about a year, nothing there. lost about 50 lbs and in relatively good health sometimes have a bit high of blood pressure but , not to often