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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does Taking Cymbalta,Clonazepam And Valproic Acid Lead To Weight Gain?

I am taking cymbalta, clonzapam, valproic acid, lamotrgine,buprioncetrazinecompridone. Do you feel that this is too many drugs to take at once. I have been having vivid dreams, fatigue, lack of motivation and weight gain. Which drugs cause weight gain?
Fri, 28 Aug 2015
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Psychiatrist 's  Response
Hello thanks for asking from HCM for your health related queries

I can understand your concern. You are currently taking Cymbalta, Clonazepam, Valproate, Lamotrigine, Bupropion, Cetrizine etc drugs.

Out of these drugs Cymbalta is Duloxetine and is a SNRI drug. The drug is known to cause weight gain in very high doses. The drug is an antidepressant drug and if used properly helps to reduce the depressive symptoms of fatigue, lack of motivation etc.

Clonazepam is a benzodiazepine drug and the drug is used for poor sleep. The drug doesn't cause much weight gain but it causes effects on sleep architecture and might result in increase in vivid dreams. So most likely the vivid dreams you are having are due to Clonazepam.

Valproate and Lamotrigine both are mood stabiliser drugs. These drugs are used in bipolar disorders. These drugs are safe to use but are known to cause weight gain and increase the appetite. Taking these drugs in high doses result in significant weight gain.

Cetrizine is an antihistaminic drug. This drug is also known to cause weight gain. The drug is known to result in tiredness, drowsiness, fatiguability etc symptoms.

If your symptoms are digressing and if these drugs are causing significant weight gain then please consult your psychiatrist for re-evaluation and change in prescription if needed.

Thanks, Hope this helps you. Take care

Dr. Seikhoo Bishnoi,
Psychiatrist.
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Does Taking Cymbalta,Clonazepam And Valproic Acid Lead To Weight Gain?

Hello thanks for asking from HCM for your health related queries I can understand your concern. You are currently taking Cymbalta, Clonazepam, Valproate, Lamotrigine, Bupropion, Cetrizine etc drugs. Out of these drugs Cymbalta is Duloxetine and is a SNRI drug. The drug is known to cause weight gain in very high doses. The drug is an antidepressant drug and if used properly helps to reduce the depressive symptoms of fatigue, lack of motivation etc. Clonazepam is a benzodiazepine drug and the drug is used for poor sleep. The drug doesn t cause much weight gain but it causes effects on sleep architecture and might result in increase in vivid dreams. So most likely the vivid dreams you are having are due to Clonazepam. Valproate and Lamotrigine both are mood stabiliser drugs. These drugs are used in bipolar disorders. These drugs are safe to use but are known to cause weight gain and increase the appetite. Taking these drugs in high doses result in significant weight gain. Cetrizine is an antihistaminic drug. This drug is also known to cause weight gain. The drug is known to result in tiredness, drowsiness, fatiguability etc symptoms. If your symptoms are digressing and if these drugs are causing significant weight gain then please consult your psychiatrist for re-evaluation and change in prescription if needed. Thanks, Hope this helps you. Take care Dr. Seikhoo Bishnoi, Psychiatrist.